N-glycosylation of human nicastrin is required for interaction with the lectins from the secretory pathway calnexin and ERGIC-53.

Morais, Vanessa A; Brito, Catarina; Pijak, Donald S; Crystal, Adam S; Fortna, Ryan R; Li, Tong; Wong, Phil C; Doms, Robert W; Costa, Júlia

Morais, Vanessa A; Brito, Catarina; Pijak, Donald S; Crystal, Adam S; Fortna, Ryan R; Li, Tong; Wong, Phil C; Doms, Robert W; Costa, Júlia.

Affiliation

Morais VA; Instituto de Tecnologia Química e Biológica/Instituto de Biologia Experimental e Tecnológica, Avenida da República, Apartado 127, 2781-901 Oeiras, Portugal.

Biochim Biophys Acta ; 1762(9): 802-10, 2006 Sep.

Article in En | MEDLINE | ID: mdl-16938437

Subject(s)

Amyloid Precursor Protein Secretases/metabolism; Calnexin/metabolism; Lectins/metabolism; Mannose-Binding Lectins/metabolism; Membrane Glycoproteins/metabolism; Membrane Proteins/metabolism; Signal Transduction; Amyloid Precursor Protein Secretases/genetics; Amyloid Precursor Protein Secretases/physiology; Animals; Cells, Cultured; Glycosylation; Humans; Membrane Glycoproteins/genetics; Mice; Oligopeptides/physiology; Oligosaccharides; Peptides; Protozoan Proteins; Transfection

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Membrane Glycoproteins / Signal Transduction / Calnexin / Mannose-Binding Lectins / Amyloid Precursor Protein Secretases / Lectins / Membrane Proteins Limits: Animals / Humans Language: En Journal: Biochim Biophys Acta Year: 2006 Document type: Article Affiliation country: Portugal Country of publication: Netherlands

Search on Google

Add to My VHL

XML

PubMed Links