Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma.

Jackson-Bernitsas, D G; Ichikawa, H; Takada, Y; Myers, J N; Lin, X L; Darnay, B G; Chaturvedi, M M; Aggarwal, B B

Jackson-Bernitsas, D G; Ichikawa, H; Takada, Y; Myers, J N; Lin, X L; Darnay, B G; Chaturvedi, M M; Aggarwal, B B.

Affiliation

Jackson-Bernitsas DG; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Oncogene ; 26(10): 1385-97, 2007 Mar 01.

Article in En | MEDLINE | ID: mdl-16953224

Subject(s)

Carcinoma, Squamous Cell/metabolism; Head and Neck Neoplasms/metabolism; NF-kappa B/biosynthesis; Cell Line, Tumor; Cell Proliferation; Humans; I-kappa B Kinase/metabolism; Receptor-Interacting Protein Serine-Threonine Kinases/metabolism; Receptors, Tumor Necrosis Factor, Type I/metabolism; Signal Transduction; TNF Receptor-Associated Death Domain Protein/metabolism; TNF Receptor-Associated Factor 2/metabolism; Transcription Factor RelA; Transforming Growth Factors/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell / NF-kappa B / Head and Neck Neoplasms Limits: Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2007 Document type: Article Affiliation country: United States Country of publication: United kingdom

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