Acute injury to superficial cortex leads to a decrease in synaptic inhibition and increase in excitation in neocortical layer V pyramidal cells.

Yang, Lie; Benardo, Larry S; Valsamis, Helen; Ling, Douglas S F

Yang, Lie; Benardo, Larry S; Valsamis, Helen; Ling, Douglas S F.

Affiliation

Yang L; Dept. of Physiology and Pharmacology, SUNY Downstate Medical Center, 450 Clarkson Ave. Box 29, Brooklyn, NY 11203, USA. lie.yang@downstate.edu

J Neurophysiol ; 97(1): 178-87, 2007 Jan.

Article in En | MEDLINE | ID: mdl-16987927

Subject(s)

Brain Injuries/physiopathology; Excitatory Postsynaptic Potentials/physiology; Inhibitory Postsynaptic Potentials/physiology; Neocortex/physiopathology; Pyramidal Cells/physiology; Synaptic Transmission/physiology; Acute Disease; Animals; Brain Injuries/complications; Brain Injuries/metabolism; Disease Models, Animal; Epilepsy/etiology; Epilepsy/metabolism; Epilepsy/physiopathology; Ion Channels/metabolism; Neocortex/metabolism; Neural Inhibition/physiology; Neural Pathways/metabolism; Neural Pathways/physiopathology; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells/metabolism; Rats; Rats, Sprague-Dawley; Receptors, AMPA/metabolism; Synapses/metabolism; Synapses/physiology; gamma-Aminobutyric Acid/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Brain Injuries / Pyramidal Cells / Synaptic Transmission / Neocortex / Excitatory Postsynaptic Potentials / Inhibitory Postsynaptic Potentials Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Neurophysiol Year: 2007 Document type: Article Affiliation country: United States Country of publication: United States

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