Sanguinarine induces apoptosis of human pancreatic carcinoma AsPC-1 and BxPC-3 cells via modulations in Bcl-2 family proteins.

Ahsan, Haseeb; Reagan-Shaw, Shannon; Breur, Jorien; Ahmad, Nihal

Ahsan, Haseeb; Reagan-Shaw, Shannon; Breur, Jorien; Ahmad, Nihal.

Affiliation

Ahsan H; Department of Dermatology, University of Wisconsin, Medical Science Center, 1300 University Avenue, Madison, Wisconsin 53706, USA.

Cancer Lett ; 249(2): 198-208, 2007 May 08.

Article in En | MEDLINE | ID: mdl-17005319

Subject(s)

Adenocarcinoma/metabolism; Alkaloids/pharmacology; Antineoplastic Agents/pharmacology; Benzophenanthridines/pharmacology; Carcinoma/metabolism; Isoquinolines/pharmacology; Pancreatic Neoplasms/metabolism; Proto-Oncogene Proteins c-bcl-2/metabolism; Adenocarcinoma/drug therapy; Apoptosis/drug effects; Carcinoma/drug therapy; Cell Cycle/drug effects; Cell Proliferation/drug effects; Cell Survival/drug effects; Female; Humans; Pancreatic Neoplasms/drug therapy; Proto-Oncogene Proteins c-bcl-2/genetics; RNA/metabolism; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Carcinoma / Adenocarcinoma / Proto-Oncogene Proteins c-bcl-2 / Alkaloids / Benzophenanthridines / Isoquinolines / Antineoplastic Agents Limits: Female / Humans Language: En Journal: Cancer Lett Year: 2007 Document type: Article Affiliation country: United States Country of publication: Ireland

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