Ivermectin selection on beta-tubulin: evidence in Onchocerca volvulus and Haemonchus contortus.

Eng, J K L; Blackhall, W J; Osei-Atweneboana, M Y; Bourguinat, C; Galazzo, D; Beech, R N; Unnasch, T R; Awadzi, K; Lubega, G W; Prichard, R K

Eng, J K L; Blackhall, W J; Osei-Atweneboana, M Y; Bourguinat, C; Galazzo, D; Beech, R N; Unnasch, T R; Awadzi, K; Lubega, G W; Prichard, R K.

Affiliation

Eng JK; Institute of Parasitology, McGill University, Sainte Anne-de-Bellevue, Quebec, Canada.

Mol Biochem Parasitol ; 150(2): 229-35, 2006 Dec.

Article in En | MEDLINE | ID: mdl-17007942

Subject(s)

Drug Resistance; Filaricides/therapeutic use; Haemonchiasis/drug therapy; Haemonchus/drug effects; Ivermectin/therapeutic use; Onchocerca volvulus/drug effects; Onchocerciasis/drug therapy; Tubulin/genetics; Africa, Western; Animals; Filaricides/pharmacology; Gene Frequency; Haemonchiasis/parasitology; Haemonchus/genetics; Humans; Ivermectin/pharmacology; Microfilariae/genetics; Microfilariae/isolation & purification; Onchocerca volvulus/genetics; Onchocerca volvulus/growth & development; Onchocerciasis/parasitology; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Sheep/parasitology; Skin/pathology

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Collection: 01-internacional Database: MEDLINE Main subject: Onchocerciasis / Tubulin / Ivermectin / Drug Resistance / Onchocerca volvulus / Filaricides / Haemonchiasis / Haemonchus Limits: Animals / Humans Country/Region as subject: Africa Language: En Journal: Mol Biochem Parasitol Year: 2006 Document type: Article Affiliation country: Canada Country of publication: Netherlands

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