The stem cell factor/c-kit receptor pathway enhances proliferation and invasion of pancreatic cancer cells.

Yasuda, Akira; Sawai, Hirozumi; Takahashi, Hiroki; Ochi, Nobuo; Matsuo, Yoichi; Funahashi, Hitoshi; Sato, Mikinori; Okada, Yuji; Takeyama, Hiromitsu; Manabe, Tadao

Yasuda, Akira; Sawai, Hirozumi; Takahashi, Hiroki; Ochi, Nobuo; Matsuo, Yoichi; Funahashi, Hitoshi; Sato, Mikinori; Okada, Yuji; Takeyama, Hiromitsu; Manabe, Tadao.

Affiliation

Yasuda A; Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, 4678601, Japan. a-yasuda@med.nagoya-cu.ac.jp

Mol Cancer ; 5: 46, 2006 Oct 18.

Article in En | MEDLINE | ID: mdl-17044945

Subject(s)

Cell Proliferation; Pancreatic Neoplasms/metabolism; Pancreatic Neoplasms/pathology; Proto-Oncogene Proteins c-kit/metabolism; Stem Cell Factor/metabolism; Aged; Benzamides; Blotting, Western; Cell Line, Tumor; Cell Proliferation/drug effects; Dose-Response Relationship, Drug; Female; Humans; Imatinib Mesylate; Immunohistochemistry; Male; Middle Aged; Neoplasm Invasiveness; Piperazines/pharmacology; Prognosis; Protein Kinase Inhibitors/pharmacology; Proto-Oncogene Proteins c-kit/drug effects; Pyrimidines/pharmacology; RNA, Messenger/analysis; Signal Transduction/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Stem Cell Factor / Proto-Oncogene Proteins c-kit / Cell Proliferation Type of study: Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Mol Cancer Journal subject: NEOPLASIAS Year: 2006 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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