Thymopentin-loaded pH-sensitive chitosan nanoparticles for oral administration: preparation, characterization, and pharmacodynamics.

Zheng, Ai-Ping; Wang, Jian-Cheng; Lu, Wan-Liang; Zhang, Xuan; Zhang, Hua; Wang, Xue-Qing; Zhang, Qiang

Zheng, Ai-Ping; Wang, Jian-Cheng; Lu, Wan-Liang; Zhang, Xuan; Zhang, Hua; Wang, Xue-Qing; Zhang, Qiang.

Affiliation

Zheng AP; Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, China.

J Nanosci Nanotechnol ; 6(9-10): 2936-44, 2006.

Article in En | MEDLINE | ID: mdl-17048501

Subject(s)

Chitosan/chemistry; Drug Carriers/chemistry; Lymphocytes/drug effects; Nanostructures/chemistry; Polymethacrylic Acids/chemistry; Thymopentin/administration & dosage; Thymopentin/pharmacokinetics; Adjuvants, Immunologic/administration & dosage; Adjuvants, Immunologic/chemistry; Adjuvants, Immunologic/pharmacokinetics; Administration, Oral; Animals; Cell Survival/drug effects; Cells, Cultured; Chemistry, Pharmaceutical/methods; Crystallization/methods; Diffusion; Hydrogen-Ion Concentration; Lymphocytes/cytology; Mice; Nanostructures/ultrastructure; Particle Size; Thymopentin/chemistry

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Collection: 01-internacional Database: MEDLINE Main subject: Polymethacrylic Acids / Drug Carriers / Lymphocytes / Thymopentin / Chitosan / Nanostructures Type of study: Diagnostic_studies Limits: Animals Language: En Journal: J Nanosci Nanotechnol Year: 2006 Document type: Article Affiliation country: China Country of publication: United States

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