Sensitisation for cisplatin-induced apoptosis by isothiocyanate E-4IB leads to signalling pathways alterations.

Bodo, J; Hunakova, L; Kvasnicka, P; Jakubikova, J; Duraj, J; Kasparkova, J; Sedlak, J

Bodo, J; Hunakova, L; Kvasnicka, P; Jakubikova, J; Duraj, J; Kasparkova, J; Sedlak, J.

Affiliation

Bodo J; 1Laboratory of Tumour Immunology, Cancer Research Institute, Slovak Academy of Sciences, Vlarska 7, Bratislava, Slovakia.

Br J Cancer ; 95(10): 1348-53, 2006 Nov 20.

Article in En | MEDLINE | ID: mdl-17060935

Subject(s)

Antineoplastic Agents/pharmacology; Apoptosis/drug effects; Butyrates/pharmacology; Cisplatin/pharmacology; Isothiocyanates/pharmacology; Ovarian Neoplasms/pathology; Signal Transduction/drug effects; Blotting, Western; Caspase 3/metabolism; Cell Cycle Proteins/metabolism; Cell Proliferation/drug effects; Drug Synergism; Drug Therapy, Combination; Female; Glutathione; Humans; Membrane Potentials/drug effects; Mitochondria/drug effects; Ovarian Neoplasms/drug therapy; Protein Kinases/metabolism; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Butyrates / Signal Transduction / Cisplatin / Apoptosis / Isothiocyanates / Antineoplastic Agents Limits: Female / Humans Language: En Journal: Br J Cancer Year: 2006 Document type: Article Affiliation country: Slovakia

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