A chaperone-mediated approach to enzyme enhancement as a therapeutic option for the lysosomal storage disorders.

Pastores, Gregory M; Sathe, Swati

Pastores, Gregory M; Sathe, Swati.

Affiliation

Pastores GM; Neurogenetics Unit, Departments of Neurology and Pediatrics, New York University School of Medicine, New York, New York 10016, USA. gregory.pastores@med.nyu.edu

Drugs R D ; 7(6): 339-48, 2006.

Article in En | MEDLINE | ID: mdl-17073517

Subject(s)

Lysosomal Storage Diseases/drug therapy; Molecular Chaperones/therapeutic use; Animals; Glycosphingolipids/metabolism; Humans; Lysosomal Storage Diseases/metabolism; Lysosomal Storage Diseases/physiopathology; Models, Biological; Molecular Chaperones/physiology; Sphingolipidoses/drug therapy; Sphingolipidoses/metabolism; Sphingolipidoses/physiopathology

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Collection: 01-internacional Database: MEDLINE Main subject: Lysosomal Storage Diseases / Molecular Chaperones Type of study: Clinical_trials / Prognostic_studies Limits: Animals / Humans Language: En Journal: Drugs R D Journal subject: TERAPIA POR MEDICAMENTOS Year: 2006 Document type: Article Affiliation country: United States Country of publication: New Zealand

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