Activity and regulation of factor VIIa analogs with increased potency at the endothelial cell surface.

Ghosh, S; Ezban, M; Persson, E; Pendurthi, U; Hedner, U; Rao, L V M

Ghosh, S; Ezban, M; Persson, E; Pendurthi, U; Hedner, U; Rao, L V M.

Affiliation

Ghosh S; Biomedical Research Division, The University of Texas Health Center at Tyler, Tyler, TX 75708, USA.

J Thromb Haemost ; 5(2): 336-46, 2007 Feb.

Article in En | MEDLINE | ID: mdl-17092304

Subject(s)

Endothelium, Vascular/drug effects; Factor VII/chemistry; Factor VII/pharmacology; Annexin A5/pharmacology; Antithrombin III/pharmacology; Cells, Cultured; Endothelial Cells/drug effects; Endothelium, Vascular/cytology; Factor VII/antagonists & inhibitors; Factor VIIa; Factor Xa/biosynthesis; Humans; Lipoproteins/pharmacology; Recombinant Proteins/antagonists & inhibitors; Recombinant Proteins/chemistry; Recombinant Proteins/pharmacology; Structure-Activity Relationship; Thrombin/biosynthesis; Thromboplastin/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Factor VII / Endothelium, Vascular Limits: Humans Language: En Journal: J Thromb Haemost Journal subject: HEMATOLOGIA Year: 2007 Document type: Article Affiliation country: United States Country of publication: United kingdom

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