Insulin and glucagon levels in fulminant hepatic failure in man.
Dig Dis Sci
; 36(6): 801-8, 1991 Jun.
Article
in En
| MEDLINE
| ID: mdl-1709604
ABSTRACT
The behavior of insulin and glucagon and related metabolic substrates was assayed in plasma of patients with fulminant hepatic failure. All 12 subjects were provided the same nutritional support. High levels of insulin and glucagon were present at all times and no difference was observed between surviving patients (four) and those who died (8). Elevated values for branched-chain and aromatic amino acids as well as alanine were present. Statistically significant lower levels of aromatic amino acids and consequently a greater branched chain-aromatic amino acid ratio was found in surviving vs nonsurviving patients. A significantly greater level of alpha-fetoprotein was found in patients who survived as compared to those who died.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Glucagon
/
Insulin
/
Liver Diseases
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
Dig Dis Sci
Year:
1991
Document type:
Article
Affiliation country:
Italy