Endothelial nitric oxide synthase activation leads to dilatory H2O2 production in mouse cerebral arteries.

Drouin, Annick; Thorin-Trescases, Nathalie; Hamel, Edith; Falck, John R; Thorin, Eric

Drouin, Annick; Thorin-Trescases, Nathalie; Hamel, Edith; Falck, John R; Thorin, Eric.

Affiliation

Drouin A; Université de Montréal, Department of Surgery and Research Center, Institut de Cardiologie de Montréal, Montréal, Québec, Canada.

Cardiovasc Res ; 73(1): 73-81, 2007 Jan 01.

Article in En | MEDLINE | ID: mdl-17113574

Subject(s)

Cerebral Arteries; Endothelium, Vascular/enzymology; Hydrogen Peroxide/metabolism; Nitric Oxide Synthase Type III/metabolism; Vasodilation/physiology; Acetylcholine/pharmacology; Animals; Bradykinin/pharmacology; Calcium Channel Blockers/pharmacology; Catalase/pharmacology; Cells, Cultured; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors/pharmacology; Free Radical Scavengers/pharmacology; Guanylate Cyclase/antagonists & inhibitors; Hydrogen Peroxide/pharmacology; Male; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Nitric Oxide/metabolism; Nitric Oxide Synthase Type III/analysis; Nitroarginine/pharmacology; Polyethylene Glycols/pharmacology; Pyruvic Acid/pharmacology; Reactive Oxygen Species/analysis; Reactive Oxygen Species/metabolism; Vasodilation/drug effects; Vasodilator Agents/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Vasodilation / Endothelium, Vascular / Cerebral Arteries / Nitric Oxide Synthase Type III / Hydrogen Peroxide Limits: Animals Language: En Journal: Cardiovasc Res Year: 2007 Document type: Article Affiliation country: Canada Country of publication: United kingdom

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