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1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile.
Fancelli, Daniele; Moll, Jürgen; Varasi, Mario; Bravo, Rodrigo; Artico, Roberta; Berta, Daniela; Bindi, Simona; Cameron, Alexander; Candiani, Ilaria; Cappella, Paolo; Carpinelli, Patrizia; Croci, Walter; Forte, Barbara; Giorgini, Maria Laura; Klapwijk, Jan; Marsiglio, Aurelio; Pesenti, Enrico; Rocchetti, Maurizio; Roletto, Fulvia; Severino, Dino; Soncini, Chiara; Storici, Paola; Tonani, Roberto; Zugnoni, Paola; Vianello, Paola.
Affiliation
  • Fancelli D; Nerviano Medical Sciences S.r.l. viale Pasteur 10, 20014 Nerviano, Milan, Italy.
J Med Chem ; 49(24): 7247-51, 2006 Nov 30.
Article in En | MEDLINE | ID: mdl-17125279
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Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyrroles / Protein Serine-Threonine Kinases / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2006 Document type: Article Affiliation country: Italy Country of publication: United States
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Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyrroles / Protein Serine-Threonine Kinases / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2006 Document type: Article Affiliation country: Italy Country of publication: United States