[Mechanism of the antimutagenic effect of interferon in human fibroblasts based on induced protein analysis]. / K mekhanizmu antimutagennogo deistviia interferona v fibroblastakh cheloveka na osnove analiza indutsirovannykh belkov.

Proteins induced in human fibroblasts after treatment of some antimutagens (interferon, p-aminobenzoic acid, heating and vaccinia virus infection) were identified by means of polyacrylamide gel electrophoresis (10-15%) followed by fluorography of the gel. Influenza virus proteins (A/WSN/33) were used as markers to determine the molecular weights of the new proteins. The results obtained suggest that interferon, p-aminobenzoic acid, heating and vaccinia virus infection induced proteins with mol. weights of 24 and 18 kD except the protein with 76 kD observed only after heating insult.