Clinical findings, diagnostic approach, and outcome of Brucella melitensis epididymo-orchitis.
Diagn Microbiol Infect Dis
; 57(4): 367-72, 2007 Apr.
Article
in En
| MEDLINE
| ID: mdl-17141451
ABSTRACT
We have studied 912 patients with brucellosis. Of these, 631 (69.2%) were male and 48 had epididymo-orchitis, giving an incidence of epididymo-orchitis of 7.6%. The duration of symptoms before diagnosis was 52.5 +/- 70 days. All the patients had fever, swelling, and scrotal pain, but only 2 (4.2%) reported urinary symptoms. Seven patients (14.5%) had leukocyte figures above 11 x 10(9)/L, and urine analysis was normal in 69% of the patients. Blood cultures were positive in 65.8% of cases. A total of 33 patients (68.8%) received a combination of doxycycline plus streptomycin and 13 (27.1%) doxycycline plus rifampin. The overall percentage of failure or relapse was 8.8% 7.1% in the doxycycline plus streptomycin group and 20% in the doxycycline plus rifampin group. None of the patients required surgery. Pending clinical trials to confirm the results, conservative management with a combination of doxycycline for 2 months and streptomycin for 14 to 21 days appears to be adequate and could avoid unnecessary orchiectomy.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Orchitis
/
Brucellosis
/
Brucella melitensis
/
Epididymitis
/
Anti-Bacterial Agents
Type of study:
Diagnostic_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Diagn Microbiol Infect Dis
Year:
2007
Document type:
Article
Affiliation country:
Spain