Enhanced AT1 receptor-mediated vasocontractile response to ANG II in endothelium-denuded aorta of obese Zucker rats.

Siddiqui, Athar H; Hussain, Tahir

Enhanced AT1 receptor-mediated vasocontractile response to ANG II in endothelium-denuded aorta of obese Zucker rats.

Siddiqui, Athar H; Hussain, Tahir.

Affiliation

Siddiqui AH; Department of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, Texas 77204-5037, USA.

Am J Physiol Heart Circ Physiol ; 292(4): H1722-7, 2007 Apr.

Article in En | MEDLINE | ID: mdl-17142345

Subject(s)

Angiotensin II/pharmacology; Muscle, Smooth, Vascular/physiology; Obesity/physiopathology; Receptor, Angiotensin, Type 1/metabolism; Vasoconstriction/physiology; Vasoconstrictor Agents/pharmacology; Acetylcholine/pharmacology; Angiotensin II Type 1 Receptor Blockers/pharmacology; Animals; Aorta, Thoracic/cytology; Body Weight; Endothelial Cells; Endothelin-1/pharmacology; Enzyme Inhibitors/pharmacology; In Vitro Techniques; Losartan/pharmacology; Male; Muscle, Smooth, Vascular/cytology; Muscle, Smooth, Vascular/drug effects; NG-Nitroarginine Methyl Ester/pharmacology; Nitric Oxide Synthase Type III/metabolism; Nitroprusside/pharmacology; Obesity/metabolism; Potassium Chloride/pharmacology; RNA, Messenger/metabolism; Rats; Rats, Zucker; Receptor, Angiotensin, Type 1/genetics; Vasoconstriction/drug effects; Vasodilator Agents/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Vasoconstriction / Vasoconstrictor Agents / Angiotensin II / Receptor, Angiotensin, Type 1 / Muscle, Smooth, Vascular / Obesity Type of study: Prognostic_studies Limits: Animals Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2007 Document type: Article Affiliation country: United States Country of publication: United States

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