[Experimental study on anti-tumor effect of extractive from Celastrus orbiculatus in vivo].
Zhongguo Zhong Yao Za Zhi
; 31(18): 1514-6, 2006 Sep.
Article
in Zh
| MEDLINE
| ID: mdl-17144469
ABSTRACT
OBJECTIVE:
To study the anti-tumor activity of extractive from Celastrus orbiculatus in vivo.METHOD:
Mice bearing transplanted tumor S180 and Heps were used to study the effects of acetoacetate and n-butanol extractive from C. orbiculatus. The changes in serum contents of SOD and malondialdehyde (MDA) content were assayed.RESULT:
Acetoacetate and n-butanol extractive from C. orbiculatus significantly inhibited the growth of S180 and Heps tumor in mice. SOD content was obviously increased, MDA content obviously decreased in the serum after extractive treatment.CONCLUSION:
Acetoacetate and n-butanol extractive from C. orbiculatus have anti-tumor effects and anti-oxidative capacity.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sarcoma 180
/
Drugs, Chinese Herbal
/
Celastrus
/
Antineoplastic Agents, Phytogenic
Limits:
Animals
Language:
Zh
Journal:
Zhongguo Zhong Yao Za Zhi
Journal subject:
FARMACOLOGIA
/
TERAPIAS COMPLEMENTARES
Year:
2006
Document type:
Article
Affiliation country:
China