Integrity and barrier function of the epidermis critically depend on glucosylceramide synthesis.

Jennemann, Richard; Sandhoff, Roger; Langbein, Lutz; Kaden, Sylvia; Rothermel, Ulrike; Gallala, Hichem; Sandhoff, Konrad; Wiegandt, Herbert; Gröne, Hermann-Josef

Jennemann, Richard; Sandhoff, Roger; Langbein, Lutz; Kaden, Sylvia; Rothermel, Ulrike; Gallala, Hichem; Sandhoff, Konrad; Wiegandt, Herbert; Gröne, Hermann-Josef.

Affiliation

Jennemann R; Department of Cellular und Molecular Pathology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. r.jennemann@dkfz.de

J Biol Chem ; 282(5): 3083-94, 2007 Feb 02.

Article in En | MEDLINE | ID: mdl-17145749

Subject(s)

Epidermis/physiology; Glucosylceramides/biosynthesis; Glucosyltransferases/genetics; Animals; Base Sequence; Epidermis/enzymology; Exons; Genotype; Glucosyltransferases/deficiency; Glucosyltransferases/metabolism; Lipids/isolation & purification; Mice; Mice, Knockout; Polymerase Chain Reaction; RNA, Messenger/genetics; RNA, Messenger/isolation & purification; Skin Physiological Phenomena

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Collection: 01-internacional Database: MEDLINE Main subject: Epidermis / Glucosylceramides / Glucosyltransferases Limits: Animals Language: En Journal: J Biol Chem Year: 2007 Document type: Article Affiliation country: Germany

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