Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A.

Flanagan, W M; Corthésy, B; Bram, R J; Crabtree, G R

Flanagan, W M; Corthésy, B; Bram, R J; Crabtree, G R.

Affiliation

Flanagan WM; Beckman Center for Molecular and Genetic Medicine, Howard Hughes Medical Institute, Stanford University Medical School, California 94305.

Nature ; 352(6338): 803-7, 1991 Aug 29.

Article in En | MEDLINE | ID: mdl-1715516

Subject(s)

Anti-Bacterial Agents/pharmacology; Cell Nucleus/metabolism; Cyclosporins/pharmacology; T-Lymphocytes/ultrastructure; Transcription Factors/metabolism; Amino Acid Isomerases/antagonists & inhibitors; Amino Acid Isomerases/metabolism; Animals; Calcium/metabolism; Carrier Proteins/antagonists & inhibitors; Carrier Proteins/metabolism; Cell Nucleus/drug effects; Cytoplasm/metabolism; DNA/metabolism; Humans; Hybridomas/metabolism; Hybridomas/ultrastructure; Ionomycin/pharmacology; Mice; Peptidylprolyl Isomerase; Polyenes/pharmacology; Sirolimus; T-Lymphocytes/drug effects; T-Lymphocytes/metabolism; Tacrolimus; Transcription, Genetic/drug effects; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / T-Lymphocytes / Cell Nucleus / Cyclosporins / Anti-Bacterial Agents Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: Nature Year: 1991 Document type: Article Country of publication: United kingdom

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