Alcohol regulates eukaryotic elongation factor 2 phosphorylation via an AMP-activated protein kinase-dependent mechanism in C2C12 skeletal myocytes.

Hong-Brown, Ly Q; Brown, C Randell; Huber, Danuta S; Lang, Charles H

Hong-Brown, Ly Q; Brown, C Randell; Huber, Danuta S; Lang, Charles H.

Affiliation

Hong-Brown LQ; Department of Cellular and Molecular Physiology, Penn State University College of Medicine, Hershey, Pennsylvania 17033, USA. lqh10@psu.edu

J Biol Chem ; 282(6): 3702-12, 2007 Feb 09.

Article in En | MEDLINE | ID: mdl-17164244

Subject(s)

Calcium-Calmodulin-Dependent Protein Kinases/metabolism; Ethanol/pharmacology; Multienzyme Complexes/physiology; Muscle Cells/enzymology; Muscle, Skeletal/enzymology; Protein Serine-Threonine Kinases/physiology; AMP-Activated Protein Kinases; Animals; Calcium-Calmodulin-Dependent Protein Kinases/antagonists & inhibitors; Cell Line; Elongation Factor 2 Kinase; Ethanol/chemistry; Mice; Muscle Cells/drug effects; Muscle Cells/metabolism; Muscle, Skeletal/drug effects; Muscle, Skeletal/metabolism; Phosphorylation/drug effects; Protein Synthesis Inhibitors/chemistry; Protein Synthesis Inhibitors/pharmacology; Signal Transduction/drug effects; Signal Transduction/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Protein Serine-Threonine Kinases / Calcium-Calmodulin-Dependent Protein Kinases / Muscle, Skeletal / Muscle Cells / Ethanol / Multienzyme Complexes Limits: Animals Language: En Journal: J Biol Chem Year: 2007 Document type: Article Affiliation country: United States Country of publication: United States

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