Selection-by-function: efficient enrichment of cathepsin E inhibitors from a DNA library.

Naimuddin, Mohammed; Kitamura, Koichirou; Kinoshita, Yasunori; Honda-Takahashi, Yoko; Murakami, Marina; Ito, Masato; Yamamoto, Kenji; Hanada, Kazunori; Husimi, Yuzuru; Nishigaki, Koichi

Naimuddin, Mohammed; Kitamura, Koichirou; Kinoshita, Yasunori; Honda-Takahashi, Yoko; Murakami, Marina; Ito, Masato; Yamamoto, Kenji; Hanada, Kazunori; Husimi, Yuzuru; Nishigaki, Koichi.

Affiliation

Naimuddin M; Rational Evolutionary Design of Advanced Biomolecules (REDS), Saitama Small Enterprise Promotion Corporation, SKIP city, 3-12-18 Kamiaoki, Kawaguchi, Saitama 333-0844, Japan. naimuddin@janusys.co.jp

J Mol Recognit ; 20(1): 58-68, 2007.

Article in En | MEDLINE | ID: mdl-17173335

Subject(s)

Cathepsin E/antagonists & inhibitors; Gene Library; Protease Inhibitors/pharmacology; SELEX Aptamer Technique/methods; Amino Acid Sequence; Animals; Aptamers, Peptide/chemistry; Base Sequence; Cathepsin D/antagonists & inhibitors; DNA/chemistry; DNA/genetics; Kinetics; Molecular Sequence Data; Nucleic Acid Conformation; Rats; Substrate Specificity

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Collection: 01-internacional Database: MEDLINE Main subject: Protease Inhibitors / Gene Library / Cathepsin E / SELEX Aptamer Technique Limits: Animals Language: En Journal: J Mol Recognit Journal subject: BIOLOGIA MOLECULAR Year: 2007 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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