The role of PKCzeta in amikacin-induced apoptosis in the cochlea: prevention by aspirin.

Lecain, Eric; Omri, Boubaker; Behar-Cohen, Francine; Tran Ba Huy, Patrice; Crisanti, Patricia

Lecain, Eric; Omri, Boubaker; Behar-Cohen, Francine; Tran Ba Huy, Patrice; Crisanti, Patricia.

Affiliation

Lecain E; Hôpital Lariboisière, Service ORL, 2 rue Ambroise Paré, 75010, Paris, France.

Apoptosis ; 12(2): 333-42, 2007 Feb.

Article in En | MEDLINE | ID: mdl-17191118

Subject(s)

Amikacin/pharmacology; Apoptosis/drug effects; Aspirin/pharmacology; Cochlea/cytology; Cochlea/enzymology; Protein Kinase C/metabolism; Animals; Anti-Bacterial Agents/pharmacology; Anti-Inflammatory Agents, Non-Steroidal/pharmacology; Apoptosis Inducing Factor/metabolism; Audiometry, Evoked Response; Cell Nucleus/drug effects; Cell Nucleus/metabolism; Male; Protein Transport/drug effects; Rats; Rats, Inbred Lew; Spiral Ganglion/cytology; Spiral Ganglion/drug effects; Spiral Ganglion/metabolism; Subcellular Fractions/drug effects; Subcellular Fractions/enzymology; Transcription Factor RelA/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase C / Amikacin / Aspirin / Cochlea / Apoptosis Limits: Animals Language: En Journal: Apoptosis Year: 2007 Document type: Article Affiliation country: France Country of publication: Netherlands

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