Three-dimensional cartilage tissue engineering using adult stem cells from osteoarthritis patients.

Kafienah, Wael; Mistry, Sanjay; Dickinson, Sally C; Sims, Trevor J; Learmonth, Ian; Hollander, Anthony P

Kafienah, Wael; Mistry, Sanjay; Dickinson, Sally C; Sims, Trevor J; Learmonth, Ian; Hollander, Anthony P.

Affiliation

Kafienah W; Southmead Hospital, and University of Bristol, Bristol, UK.

Arthritis Rheum ; 56(1): 177-87, 2007 Jan.

Article in En | MEDLINE | ID: mdl-17195220

Subject(s)

Hyaline Cartilage/cytology; Mesenchymal Stem Cells/cytology; Osteoarthritis, Hip/pathology; Parathyroid Hormone-Related Protein/pharmacology; Tissue Engineering/methods; Transforming Growth Factors/pharmacology; Adult; Aged; Aged, 80 and over; Animals; Bone Marrow Cells/cytology; Bone Marrow Cells/drug effects; Bone Marrow Cells/physiology; Cattle; Cells, Cultured; Collagen Type I/genetics; Collagen Type I/metabolism; Collagen Type II/genetics; Collagen Type II/metabolism; Dose-Response Relationship, Drug; Drug Combinations; Female; Gene Expression/drug effects; Humans; Hyaline Cartilage/metabolism; Male; Mesenchymal Stem Cells/drug effects; Mesenchymal Stem Cells/physiology; Middle Aged; Proteoglycans/genetics; Proteoglycans/metabolism; RNA, Messenger/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis, Hip / Transforming Growth Factors / Tissue Engineering / Parathyroid Hormone-Related Protein / Hyaline Cartilage / Mesenchymal Stem Cells Limits: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: Arthritis Rheum Year: 2007 Document type: Article Affiliation country: United kingdom Country of publication: United States

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