The carboxyl terminal amino acid residues of Pseudomonas aeruginosa exotoxin A involved in cell toxicity and pathogenesis, characterized by a neutralizing human monoclonal antibody.

Ohtsuka, H; Higuchi, A; Nomura, N; Horigome, K; Kohzuki, T; Nakamori, Y; Noguchi, H

Ohtsuka, H; Higuchi, A; Nomura, N; Horigome, K; Kohzuki, T; Nakamori, Y; Noguchi, H.

Affiliation

Ohtsuka H; Biotechnology Laboratory, Sumitomo Chemical Co., Ltd., Hyogo, Japan.

Biochem Biophys Res Commun ; 180(3): 1498-504, 1991 Nov 14.

Article in En | MEDLINE | ID: mdl-1719985

Subject(s)

ADP Ribose Transferases; Antibodies, Monoclonal; Bacterial Toxins; Carrier Proteins; Cell Survival/drug effects; Exotoxins/toxicity; Pseudomonas Infections/immunology; Pseudomonas aeruginosa/pathogenicity; Receptors, Cell Surface; Virulence Factors; 3T3 Cells; Animals; Antibodies, Monoclonal/therapeutic use; Chromosome Deletion; Enzyme-Linked Immunosorbent Assay; Epitopes/analysis; Exotoxins/genetics; Exotoxins/immunology; Genes, Bacterial; Humans; Immunotherapy; Male; Mice; Mice, Inbred ICR; Neutralization Tests; Peptide Fragments/isolation & purification; Peptide Fragments/metabolism; Poly(ADP-ribose) Polymerase Inhibitors; Receptors, Cholinergic/metabolism; Recombinant Proteins/immunology; Recombinant Proteins/toxicity; Pseudomonas aeruginosa Exotoxin A

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Pseudomonas aeruginosa / Pseudomonas Infections / Bacterial Toxins / Carrier Proteins / Cell Survival / ADP Ribose Transferases / Receptors, Cell Surface / Virulence Factors / Exotoxins / Antibodies, Monoclonal Type of study: Etiology_studies Limits: Animals / Humans / Male Language: En Journal: Biochem Biophys Res Commun Year: 1991 Document type: Article Affiliation country: Japan Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links