Augmented lipopolysaccharide-induced TNF-alpha production by peritoneal macrophages in type 2 diabetic mice is dependent on elevated glucose and requires p38 MAPK.

Sherry, Christina L; O'Connor, Jason C; Kramer, Jason M; Freund, Gregory G

Sherry, Christina L; O'Connor, Jason C; Kramer, Jason M; Freund, Gregory G.

Affiliation

Sherry CL; Division of Nutritional Sciences, Integrative Immunology and Behavior Program, University of Illinois, 506 South Mathews Avenue, Urbana, IL 61801, USA.

J Immunol ; 178(2): 663-70, 2007 Jan 15.

Article in En | MEDLINE | ID: mdl-17202326

Subject(s)

Diabetes Mellitus, Type 2/metabolism; Glucose/metabolism; Lipopolysaccharides/pharmacology; Macrophages, Peritoneal/drug effects; Macrophages, Peritoneal/metabolism; Tumor Necrosis Factor-alpha/biosynthesis; p38 Mitogen-Activated Protein Kinases/metabolism; Animals; Enzyme Activation/drug effects; Mice; Mitogen-Activated Protein Kinase 1/metabolism; Mitogen-Activated Protein Kinase 3/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Phosphorylation/drug effects; Tumor Necrosis Factor-alpha/metabolism

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Lipopolysaccharides / Tumor Necrosis Factor-alpha / Macrophages, Peritoneal / P38 Mitogen-Activated Protein Kinases / Diabetes Mellitus, Type 2 / Glucose Limits: Animals Language: En Journal: J Immunol Year: 2007 Document type: Article Affiliation country: United States Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links