Three-component, one-pot synthesis of 2,4,5-substituted pyrimidines library for screening against human hepatocellular carcinoma BEL-7402 cells.

Xie, Fuchun; Li, Shukun; Bai, Donglu; Lou, Liguang; Hu, Youhong

Xie, Fuchun; Li, Shukun; Bai, Donglu; Lou, Liguang; Hu, Youhong.

Affiliation

Xie F; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China.

J Comb Chem ; 9(1): 12-3, 2007.

Article in En | MEDLINE | ID: mdl-17206826

Subject(s)

Antineoplastic Agents/chemical synthesis; Antineoplastic Agents/pharmacology; Pyrimidines/chemical synthesis; Pyrimidines/pharmacology; Amidines/chemistry; Boronic Acids/chemistry; Carcinoma, Hepatocellular/drug therapy; Cell Line, Tumor; Chromones/chemistry; Combinatorial Chemistry Techniques/methods; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Liver Neoplasms/drug therapy; Molecular Structure

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Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Antineoplastic Agents Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: J Comb Chem Journal subject: QUIMICA Year: 2007 Document type: Article Affiliation country: China

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