Cellulose biosynthesis pathway is a potential target in the improved treatment of Acanthamoeba keratitis.

Dudley, Ricky; Alsam, Selwa; Khan, Naveed Ahmed

Dudley, Ricky; Alsam, Selwa; Khan, Naveed Ahmed.

Affiliation

Dudley R; School of Biological and Chemical Sciences, Birkbeck College, University of London, London, England, UK.

Appl Microbiol Biotechnol ; 75(1): 133-40, 2007 May.

Article in En | MEDLINE | ID: mdl-17225099

Subject(s)

Acanthamoeba Keratitis/drug therapy; Acanthamoeba castellanii/drug effects; Amebicides/pharmacology; Cellulose/biosynthesis; Nitriles/pharmacology; Pentamidine/pharmacology; Acanthamoeba Keratitis/parasitology; Acanthamoeba castellanii/growth & development; Acanthamoeba castellanii/isolation & purification; Acanthamoeba castellanii/metabolism; Amebicides/toxicity; Animals; Brain/blood supply; Cells, Cultured; Cellulose/antagonists & inhibitors; Drug Synergism; Endothelium, Vascular/cytology; Humans; Microcirculation; Nitriles/toxicity; Pentamidine/toxicity

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Collection: 01-internacional Database: MEDLINE Main subject: Pentamidine / Acanthamoeba Keratitis / Cellulose / Acanthamoeba castellanii / Amebicides / Nitriles Type of study: Screening_studies Limits: Animals / Humans Language: En Journal: Appl Microbiol Biotechnol Year: 2007 Document type: Article Affiliation country: United kingdom Country of publication: Germany

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