Structure-activity relationships of novel piperazines as antagonists for the melanocortin-4 receptor.

Nozawa, Dai; Okubo, Taketoshi; Ishii, Takaaki; Kakinuma, Hiroyuki; Chaki, Shigeyuki; Okuyama, Shigeru; Nakazato, Atsuro

Nozawa, Dai; Okubo, Taketoshi; Ishii, Takaaki; Kakinuma, Hiroyuki; Chaki, Shigeyuki; Okuyama, Shigeru; Nakazato, Atsuro.

Affiliation

Nozawa D; Medicinal Research Laboratories, Taisho Pharmaceutical Co., Ltd, 1-403 Yoshino-cho, Kita-ku, Saitama, Saitama 331-9530, Japan. dai.nozawa@po.rd.taisho.co.jp

Bioorg Med Chem ; 15(5): 1989-2005, 2007 Mar 01.

Article in En | MEDLINE | ID: mdl-17234422

Subject(s)

Piperazines/chemistry; Piperazines/pharmacology; Receptor, Melanocortin, Type 4/antagonists & inhibitors; Animals; COS Cells; Chlorocebus aethiops; Magnetic Resonance Spectroscopy; Rats; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Receptor, Melanocortin, Type 4 Limits: Animals Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2007 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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