Enzymatic removal of carboxyl protecting groups. III. Fast removal of allyl and chloroethyl esters by Bacillus subtilis esterase (BS2).
J Org Chem
; 72(3): 782-6, 2007 Feb 02.
Article
in En
| MEDLINE
| ID: mdl-17253795
ABSTRACT
An esterase from Bacillus subtilis (BS2) allows the fast and selective removal of allyl, 2-chloroethyl, and 2,2,2-chloroethyl esters under mild conditions in high yields. In addition, BS2 easily hydrolyzes phenacyl esters, while the hydrolysis of sterically hindered diphenylmethyl esters is slow, requiring longer reaction time and higher enzyme/substrate ratio.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bacillus subtilis
/
Carboxylic Acids
/
Allyl Compounds
/
Esterases
/
Esters
/
Ethyl Chloride
Language:
En
Journal:
J Org Chem
Year:
2007
Document type:
Article
Affiliation country:
Greece