Factors associated with health-related quality of life among hemodialysis patients in the DOPPS.
Qual Life Res
; 16(4): 545-57, 2007 May.
Article
in En
| MEDLINE
| ID: mdl-17286199
ABSTRACT
OBJECTIVE:
To identify modifiable factors associated with health-related quality of life (HRQOL) among chronic hemodialysis patients.METHODS:
Analysis of baseline data of 9,526 hemodialysis patients from seven countries enrolled in phase I of the Dialysis Outcomes and Practice Patterns Study (DOPPS). Using the Kidney Disease Quality of Life Short Form (KDQOL-SF(TM)), we determined scores for 8 generic scale summaries derived from these scales, i.e., the physical component summary [PCS] and mental component summary [MCS], and 11 kidney disease- targeted scales. Regression models were used to adjust for differences in comorbidities and sociodemographic and treatment factors. The Benjamini-Hochberg procedure was used to correct P-values for multiple comparisons.RESULTS:
Unemployment and psychiatric disease were independently and significantly associated with lower scores for all generic and several kidney disease-targeted HRQOL measures. Several other comorbidities, lower educational level, lower income, and hypoalbuminemia were also independently and significantly associated with lower scores of PCS and/or MCS and several generic and kidney disease-targeted scales. Hemodialysis by catheter was associated with significantly lower PCS scores, partially explained by the correlation with covariates.CONCLUSION:
Associations of poorer HRQOL with preventable or controllable factors support a greater focus on psychosocial and medical interventions to improve the well-being of hemodialysis patients.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Quality of Life
/
Renal Dialysis
/
Sickness Impact Profile
/
Kidney Failure, Chronic
Type of study:
Clinical_trials
/
Prognostic_studies
/
Qualitative_research
/
Risk_factors_studies
Aspects:
Patient_preference
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
America do norte
/
Asia
/
Europa
Language:
En
Journal:
Qual Life Res
Journal subject:
REABILITACAO
/
TERAPEUTICA
Year:
2007
Document type:
Article
Affiliation country:
Brazil