Cross-reactive HIV-1 neutralizing monoclonal antibodies selected by screening of an immune human phage library against an envelope glycoprotein (gp140) isolated from a patient (R2) with broadly HIV-1 neutralizing antibodies.

Choudhry, Vidita; Zhang, Mei-Yun; Sidorov, Igor A; Louis, John M; Harris, Ilia; Dimitrov, Antony S; Bouma, Peter; Cham, Fatim; Choudhary, Anil; Rybak, Susanna M; Fouts, Timothy; Montefiori, David C; Broder, Christopher C; Quinnan, Gerald V; Dimitrov, Dimiter S

Choudhry, Vidita; Zhang, Mei-Yun; Sidorov, Igor A; Louis, John M; Harris, Ilia; Dimitrov, Antony S; Bouma, Peter; Cham, Fatim; Choudhary, Anil; Rybak, Susanna M; Fouts, Timothy; Montefiori, David C; Broder, Christopher C; Quinnan, Gerald V; Dimitrov, Dimiter S.

Affiliation

Choudhry V; Protein Interactions Group, CCRNP, NCI-Frederick, NIH, Frederick, MD 21702, USA.

Virology ; 363(1): 79-90, 2007 Jun 20.

Article in En | MEDLINE | ID: mdl-17306322

Subject(s)

Antibodies, Monoclonal/immunology; Cross Reactions/immunology; Gene Products, env/immunology; HIV Antibodies/immunology; HIV-1/immunology; Peptide Library; Antibodies, Monoclonal/isolation & purification; Binding, Competitive; Blotting, Western; Cell Line; Enzyme-Linked Immunosorbent Assay; HIV Envelope Protein gp120/immunology; HIV-1/classification; Humans; Immunoglobulin Fab Fragments/genetics; Immunoglobulin Fab Fragments/immunology; Neutralization Tests; env Gene Products, Human Immunodeficiency Virus

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Antibodies / Gene Products, env / HIV-1 / Peptide Library / Cross Reactions / Antibodies, Monoclonal Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Virology Year: 2007 Document type: Article Affiliation country: United States Country of publication: United States

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