Final results of a double-blind, placebo-controlled trial of the antifibrotic efficacy of interferon-gamma1b in chronic hepatitis C patients with advanced fibrosis or cirrhosis.

Pockros, Paul J; Jeffers, Lennox; Afdhal, Nezam; Goodman, Zachary D; Nelson, David; Gish, Robert G; Reddy, K Rajender; Reindollar, Robert; Rodriguez-Torres, Maribel; Sullivan, Sarah; Blatt, Lawrence M; Faris-Young, Sima

Pockros, Paul J; Jeffers, Lennox; Afdhal, Nezam; Goodman, Zachary D; Nelson, David; Gish, Robert G; Reddy, K Rajender; Reindollar, Robert; Rodriguez-Torres, Maribel; Sullivan, Sarah; Blatt, Lawrence M; Faris-Young, Sima.

Affiliation

Pockros PJ; Division of Gastroenterology/Hepatology, Scripps Clinic, La Jolla, CA 92037, USA. pockros.paul@scrippshealth.org

Hepatology ; 45(3): 569-78, 2007 Mar.

Article in En | MEDLINE | ID: mdl-17326152

Subject(s)

Antiviral Agents/therapeutic use; Hepatitis C, Chronic/drug therapy; Interferon-gamma/therapeutic use; Liver Cirrhosis/drug therapy; Adult; Aged; Antiviral Agents/adverse effects; Biomarkers/analysis; Clinical Trials, Phase II as Topic; Disease Progression; Double-Blind Method; Female; Hepacivirus/genetics; Hepatitis C, Chronic/complications; Humans; Interferon-gamma/adverse effects; Liver/metabolism; Liver/pathology; Liver Cirrhosis/etiology; Male; Middle Aged; Prospective Studies; RNA, Viral/metabolism; Recombinant Proteins

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Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Interferon-gamma / Hepatitis C, Chronic / Liver Cirrhosis Type of study: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Hepatology Year: 2007 Document type: Article Affiliation country: United States Country of publication: United States

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