siRNA delivery by a transferrin-associated lipid-based vector: a non-viral strategy to mediate gene silencing.

Cardoso, A L C; Simões, S; de Almeida, L P; Pelisek, J; Culmsee, C; Wagner, E; Pedroso de Lima, M C

Cardoso, A L C; Simões, S; de Almeida, L P; Pelisek, J; Culmsee, C; Wagner, E; Pedroso de Lima, M C.

Affiliation

Cardoso AL; Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal.

J Gene Med ; 9(3): 170-83, 2007 Mar.

Article in En | MEDLINE | ID: mdl-17351968

Subject(s)

Genetic Therapy/methods; Liposomes/chemistry; Neoplasms/therapy; RNA Interference; RNA, Small Interfering/administration & dosage; Transferrin/metabolism; Cations; Cell Line, Tumor; Fatty Acids, Monounsaturated/chemistry; Fluorescence; Gene Transfer Techniques; Genes, Reporter; Genetic Vectors/chemistry; Green Fluorescent Proteins/antagonists & inhibitors; Green Fluorescent Proteins/genetics; Humans; JNK Mitogen-Activated Protein Kinases/antagonists & inhibitors; JNK Mitogen-Activated Protein Kinases/genetics; Lipids/chemistry; Liposomes/metabolism; Quaternary Ammonium Compounds/chemistry; RNA, Small Interfering/chemistry; RNA, Small Interfering/therapeutic use; Transferrin/chemistry

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Collection: 01-internacional Database: MEDLINE Main subject: Transferrin / Genetic Therapy / RNA, Small Interfering / RNA Interference / Liposomes / Neoplasms Type of study: Risk_factors_studies Limits: Humans Language: En Journal: J Gene Med Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2007 Document type: Article Affiliation country: Portugal

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