MDL 72527 and spermine oxidation products induce a lysosomotropic effect and mitochondrial alterations in tumour cells.

Agostinelli, E; Tempera, G; Dalla Vedova, L; Condello, M; Arancia, G

Agostinelli, E; Tempera, G; Dalla Vedova, L; Condello, M; Arancia, G.

Affiliation

Agostinelli E; Department of Biochemical Sciences A Rossi Fanelli, University of Rome La Sapienza and CNR, Biology and Molecular Pathology Institutes, Piazzale Aldo Moro 5, 00185 Rome, Italy. enzo.agostinelli@uniroma1.it

Biochem Soc Trans ; 35(Pt 2): 343-8, 2007 Apr.

Article in En | MEDLINE | ID: mdl-17371275

Subject(s)

Cell Survival/drug effects; Lysosomes/physiology; Mitochondria/physiology; Putrescine/analogs & derivatives; Spermine/metabolism; Spermine/pharmacology; Animals; Cell Line, Tumor; Humans; Lysosomes/drug effects; Mitochondria/drug effects; Oxidation-Reduction; Putrescine/pharmacokinetics; Putrescine/pharmacology; Vacuoles/drug effects; Vacuoles/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Putrescine / Spermine / Cell Survival / Lysosomes / Mitochondria Limits: Animals / Humans Language: En Journal: Biochem Soc Trans Year: 2007 Document type: Article Affiliation country: Italy Country of publication: United kingdom

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