Localization of cyclooxygenase-2 in mice vas deferens and its effects on fertility upon suppression using nimesulide: a preferential cyclooxygenase-2 inhibitor.

Balaji, Thotakura; Ramanathan, Manickam; Menon, Venugopal Padmanabhan

Balaji, Thotakura; Ramanathan, Manickam; Menon, Venugopal Padmanabhan.

Affiliation

Balaji T; Department of Anatomy, Faculty of Medicine, Annamalai University, Annamalainagar, Tamilnadu, India.

Toxicology ; 234(1-2): 135-44, 2007 May 05.

Article in En | MEDLINE | ID: mdl-17382448

Subject(s)

Cyclooxygenase 2/metabolism; Fertility/drug effects; Sulfonamides/pharmacology; Vas Deferens/drug effects; Animals; Apoptosis/drug effects; Cell Nucleus/drug effects; Cell Nucleus/ultrastructure; Cyclooxygenase 1/metabolism; Cyclooxygenase 2 Inhibitors/administration & dosage; Cyclooxygenase 2 Inhibitors/pharmacology; Docosahexaenoic Acids/analysis; Eicosapentaenoic Acid; Epithelial Cells/drug effects; Epithelial Cells/metabolism; Epithelial Cells/ultrastructure; Fatty Acids, Unsaturated/analysis; Fatty Acids, Unsaturated/metabolism; Female; Immunochemistry; Litter Size/drug effects; Male; Mice; Microscopy, Electron, Transmission; Microvilli/drug effects; Microvilli/ultrastructure; Prostaglandins/metabolism; Sperm Count; Sperm Motility/drug effects; Sulfonamides/administration & dosage; Vacuoles/ultrastructure; Vas Deferens/enzymology; Vas Deferens/ultrastructure

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Vas Deferens / Cyclooxygenase 2 / Fertility Limits: Animals Language: En Journal: Toxicology Year: 2007 Document type: Article Affiliation country: India Country of publication: Ireland

Search on Google

Add to My VHL

XML

PubMed Links