Efficient synthesis of brussalexin A, a remarkable phytoalexin from Brussels sprouts.

Pedras, M Soledade C; Zheng, Qing-An; Sarwar, Mohammed G

Pedras, M Soledade C; Zheng, Qing-An; Sarwar, Mohammed G.

Affiliation

Pedras MS; Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, SK S7N 5C9, Canada. s.pedras@usask.ca

Org Biomol Chem ; 5(8): 1167-9, 2007 Apr 21.

Article in En | MEDLINE | ID: mdl-17406713

ABSTRACT

ABSTRACT

The synthesis of brussalexin A, the first phytoalexin containing an allyl thiolcarbamate group, and its selective inhibitory activity against fungal plant pathogens is described.

Subject(s)

Antifungal Agents/chemical synthesis; Brassica/chemistry; Indoles/chemical synthesis; Terpenes/chemical synthesis; Thiocarbamates/chemical synthesis; Antifungal Agents/chemistry; Antifungal Agents/pharmacology; Fungi/drug effects; Fungi/growth & development; Fungi/pathogenicity; Indoles/chemistry; Indoles/pharmacology; Microbial Sensitivity Tests; Molecular Structure; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship; Terpenes/chemistry; Terpenes/pharmacology; Thiocarbamates/chemistry; Thiocarbamates/pharmacology; Phytoalexins

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Collection: 01-internacional Database: MEDLINE Main subject: Terpenes / Thiocarbamates / Brassica / Indoles / Antifungal Agents Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2007 Document type: Article Affiliation country: Canada

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