[Second-or third-line chemotherapy with CPT-11+TS-1 for 5 cases of metastatic and recurrent colorectal cancer].
Gan To Kagaku Ryoho
; 34(4): 627-30, 2007 Apr.
Article
in Ja
| MEDLINE
| ID: mdl-17431354
ABSTRACT
The 3-drug regimen of CPT-11+5-FU+l-LV is generally used for metastatic and/or recurrent colorectal cancer. We have applied this treatment as the first-line intervention in our hospital. However,when the efficacy is reduced we try chemotherapy using CPT-11+TS-1 for 5 outpatients as second- or third-line chemotherapy. Decreased CEA levels were subsequently observed in 4 of 5 cases. In addition, 2 cases exhibited grade 1 or 2 adverse effects, but no case developed neutropenia. We could expect such effects even for patients after only 5-FU, and this treatment may be performed safely on ambulatory patients.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Colorectal Neoplasms
/
Antineoplastic Combined Chemotherapy Protocols
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
Ja
Journal:
Gan To Kagaku Ryoho
Year:
2007
Document type:
Article