In vivo antimalarial activity of isosungucine, an indolomonoterpenic alkaloid from Strychnos icaja.
Planta Med
; 73(5): 478-9, 2007 May.
Article
in En
| MEDLINE
| ID: mdl-17431825
ABSTRACT
Isosungucine (1) is a quasi-symmetric bisindolomonoterpenoid alkaloid isolated from the roots of Strychnos icaja. The in vivo antimalarial activity against the P. vinckei petteri murine strain was determined. In the Peters 4-day suppressive test, 1 suppressed the parasitemia by almost 50 percent on day 4 at the dose of 30 mg/kg by intraperitoneal route.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Indole Alkaloids
/
Strychnos
/
Antimalarials
Limits:
Animals
Language:
En
Journal:
Planta Med
Year:
2007
Document type:
Article
Affiliation country:
Belgium