Amiodarone-induced torsades de pointes: the possible facilitatory role of digoxin.
Int J Cardiol
; 33(2): 335-7, 1991 Nov.
Article
in En
| MEDLINE
| ID: mdl-1743800
ABSTRACT
Poorly controlled supraventricular arrhythmias in a hypokalaemic 74 year old woman were treated with oral amiodarone. This caused torsades de pointes, and was preceded by marked prolongation of the QT interval. The induction of torsades de pointes by amiodarone is thought to be an idiosyncratic reaction to amiodarone itself which is facilitated by electrolytic abnormalities. The present case, however, indicates the possibility of a pro-arrhythmic effect secondary to an interaction between amiodarone and digoxin.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tachycardia, Supraventricular
/
Torsades de Pointes
/
Digoxin
/
Amiodarone
/
Hypokalemia
Type of study:
Diagnostic_studies
Limits:
Aged
/
Female
/
Humans
Language:
En
Journal:
Int J Cardiol
Year:
1991
Document type:
Article
Affiliation country:
United kingdom