A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini.

Lam, Patrick P L; Hyvärinen, Kati; Kauppi, Maria; Cosen-Binker, Laura; Laitinen, Saara; Keränen, Sirkka; Gaisano, Herbert Y; Olkkonen, Vesa M

Lam, Patrick P L; Hyvärinen, Kati; Kauppi, Maria; Cosen-Binker, Laura; Laitinen, Saara; Keränen, Sirkka; Gaisano, Herbert Y; Olkkonen, Vesa M.

Affiliation

Lam PP; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

Mol Biol Cell ; 18(7): 2473-80, 2007 Jul.

Article in En | MEDLINE | ID: mdl-17442889

Subject(s)

Alternative Splicing/genetics; Amylases/metabolism; Calcium-Binding Proteins/metabolism; Cytosol/metabolism; Glycoproteins/metabolism; Munc18 Proteins/metabolism; Pancreas, Exocrine/enzymology; Alternative Splicing/drug effects; Animals; Antibodies; Bacterial Proteins/pharmacology; CHO Cells; COS Cells; Calcium/metabolism; Calcium-Binding Proteins/chemistry; Calcium-Binding Proteins/genetics; Cell Membrane Permeability/drug effects; Chlorocebus aethiops; Cricetinae; Cricetulus; Cytosol/drug effects; Dogs; EF Hand Motifs; Gene Expression Profiling; Glycoproteins/chemistry; Glycoproteins/genetics; Humans; Pancreas, Exocrine/drug effects; Pancreas, Exocrine/metabolism; Protein Binding/drug effects; RNA, Messenger/genetics; RNA, Messenger/metabolism; Rats; Streptolysins/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Calcium-Binding Proteins / Glycoproteins / Alternative Splicing / Cytosol / Pancreas, Exocrine / Munc18 Proteins / Amylases Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Biol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2007 Document type: Article Affiliation country: Canada Country of publication: United States

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