N-methyl-D-aspartate antagonists and neuropathic pain: the search for relief.

Childers, Wayne E; Baudy, Reinhardt B

Childers, Wayne E; Baudy, Reinhardt B.

Affiliation

Childers WE; Department of Chemical & Screening Sciences, Wyeth Research, Inc., CN 8000, Princeton, New Jersey 08543-8000, USA. childew@wyeth.com

J Med Chem ; 50(11): 2557-62, 2007 May 31.

Article in En | MEDLINE | ID: mdl-17489572

Subject(s)

Analgesics/pharmacology; Pain/physiopathology; Peripheral Nervous System Diseases/physiopathology; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors; Analgesics/therapeutic use; Analgesics, Opioid/pharmacology; Analgesics, Opioid/therapeutic use; Animals; Binding Sites; Glycine/metabolism; Humans; Ion Channel Gating/drug effects; Pain/drug therapy; Pain/metabolism; Peripheral Nervous System Diseases/drug therapy; Peripheral Nervous System Diseases/metabolism; Protein Subunits/antagonists & inhibitors; Protein Subunits/metabolism; Protein Subunits/physiology; Receptors, N-Methyl-D-Aspartate/metabolism; Receptors, N-Methyl-D-Aspartate/physiology

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Pain / Receptors, N-Methyl-D-Aspartate / Peripheral Nervous System Diseases / Analgesics Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2007 Document type: Article Affiliation country: United States

Search on Google

Add to My VHL

XML

PubMed Links