Mitochondria/drug effects; Oxazolidinones/pharmacology; Peptidyl Transferases/drug effects; Protein Synthesis Inhibitors/pharmacology; RNA, Ribosomal/drug effects; Software; Acetamides; Anti-Infective Agents/chemistry; Anti-Infective Agents/pharmacology; Binding Sites/drug effects; Cross-Linking Reagents/chemistry; Cross-Linking Reagents/pharmacology; Cytoplasm/drug effects; Cytoplasm/enzymology; Drug Resistance/genetics; Escherichia coli/drug effects; Escherichia coli/enzymology; Humans; Linezolid; Mitochondria/enzymology; Models, Molecular; Molecular Structure; Mutation/genetics; Oxazolidinones/chemistry; Peptidyl Transferases/metabolism; Protein Synthesis Inhibitors/chemistry; RNA, Bacterial/genetics; RNA, Bacterial/metabolism; RNA, Ribosomal/metabolism; RNA, Ribosomal, 23S; RNA, Transfer, Amino Acyl/antagonists & inhibitors; RNA, Transfer, Amino Acyl/metabolism; Staining and Labeling; Staphylococcus aureus/drug effects; Staphylococcus aureus/enzymology