Tolerability of fosaprepitant and bioequivalency to aprepitant in healthy subjects.

Lasseter, Kenneth C; Gambale, Jay; Jin, Bo; Bergman, Art; Constanzer, Marvin; Dru, James; Han, Tae H; Majumdar, Anup; Evans, Judith K; Murphy, M Gail

Lasseter, Kenneth C; Gambale, Jay; Jin, Bo; Bergman, Art; Constanzer, Marvin; Dru, James; Han, Tae H; Majumdar, Anup; Evans, Judith K; Murphy, M Gail.

Affiliation

Lasseter KC; Clinical Pharmacology Research Unit, Clinical Pharmacology of Miami, Inc, 550 West 84th Street, Hialeah, FL 33014, USA. kclasseter@gmail.com

J Clin Pharmacol ; 47(7): 834-40, 2007 Jul.

Article in En | MEDLINE | ID: mdl-17525168

Subject(s)

Antiemetics/adverse effects; Morpholines/adverse effects; Neurokinin-1 Receptor Antagonists; Prodrugs/adverse effects; Administration, Oral; Adult; Analysis of Variance; Antiemetics/administration & dosage; Antiemetics/blood; Antiemetics/pharmacokinetics; Aprepitant; Area Under Curve; Cross-Over Studies; Female; Humans; Injections, Intravenous; Male; Middle Aged; Morpholines/administration & dosage; Morpholines/blood; Morpholines/pharmacokinetics; Prodrugs/administration & dosage; Prodrugs/pharmacokinetics; Therapeutic Equivalency

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Collection: 01-internacional Database: MEDLINE Main subject: Prodrugs / Morpholines / Neurokinin-1 Receptor Antagonists / Antiemetics Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: J Clin Pharmacol Year: 2007 Document type: Article Affiliation country: United States Country of publication: United kingdom

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