Effect of lycopene on doxorubicin-induced cardiotoxicity: an echocardiographic, histological and morphometrical assessment.

Anjos Ferreira, Ana Lucia; Russell, Robert Mitchell; Rocha, Noeme; Placido Ladeira, Marcelo Sady; Favero Salvadori, Daisy Maria; Oliveira Nascimento, Maria Carolina Munhoz; Matsui, Mirna; Carvalho, Flavio Augusto; Tang, Guangwen; Matsubara, Luiz Shiguero; Matsubara, Beatriz Bojikian

Anjos Ferreira, Ana Lucia; Russell, Robert Mitchell; Rocha, Noeme; Placido Ladeira, Marcelo Sady; Favero Salvadori, Daisy Maria; Oliveira Nascimento, Maria Carolina Munhoz; Matsui, Mirna; Carvalho, Flavio Augusto; Tang, Guangwen; Matsubara, Luiz Shiguero; Matsubara, Beatriz Bojikian.

Affiliation

Anjos Ferreira AL; Department of Internal Medicine, Botucatu Faculty of Medicine, Universidade Estadual Paulista, São Paulo State University, Botucatu, SP, Brazil. ferreira@fmb.unesp.br

Basic Clin Pharmacol Toxicol ; 101(1): 16-24, 2007 Jul.

Article in En | MEDLINE | ID: mdl-17577311

Subject(s)

Antibiotics, Antineoplastic/toxicity; Antioxidants/pharmacology; Carotenoids/pharmacology; Doxorubicin/toxicity; Heart/drug effects; Animals; Antioxidants/pharmacokinetics; Carotenoids/pharmacokinetics; Chromatography, High Pressure Liquid; Electrocardiography; Lycopene; Male; Myocardium/pathology; Myocytes, Cardiac/metabolism; Random Allocation; Rats; Rats, Wistar

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Collection: 01-internacional Database: MEDLINE Main subject: Carotenoids / Doxorubicin / Heart / Antibiotics, Antineoplastic / Antioxidants Limits: Animals Language: En Journal: Basic Clin Pharmacol Toxicol Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2007 Document type: Article Affiliation country: Brazil

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