Pharmacokinetics and pharmacodynamics of efavirenz and nelfinavir in HIV-infected children participating in an area-under-the-curve controlled trial.

Fletcher, C V; Brundage, R C; Fenton, T; Alvero, C G; Powell, C; Mofenson, L M; Spector, S A

Fletcher, C V; Brundage, R C; Fenton, T; Alvero, C G; Powell, C; Mofenson, L M; Spector, S A.

Affiliation

Fletcher CV; Division of Infectious Diseases, Department of Pharmaceutical Sciences, University of Colorado Health Sciences Center, Denver, Colorado, USA. courtney.fletcher@uchsc.edu

Clin Pharmacol Ther ; 83(2): 300-6, 2008 Feb.

Article in En | MEDLINE | ID: mdl-17609682

Subject(s)

Benzoxazines/pharmacokinetics; HIV Infections/drug therapy; HIV Protease Inhibitors/pharmacokinetics; Nelfinavir/pharmacokinetics; Reverse Transcriptase Inhibitors/pharmacokinetics; Administration, Oral; Adolescent; Alkynes; Area Under Curve; Benzoxazines/administration & dosage; Cyclopropanes; Drug Therapy, Combination; HIV Infections/metabolism; HIV Infections/virology; HIV Protease Inhibitors/administration & dosage; Humans; Metabolic Clearance Rate; Nelfinavir/administration & dosage; RNA, Viral/blood; Reverse Transcriptase Inhibitors/administration & dosage; Treatment Outcome; United States; Virus Replication/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV Protease Inhibitors / Reverse Transcriptase Inhibitors / Nelfinavir / Benzoxazines Type of study: Clinical_trials / Prognostic_studies Limits: Adolescent / Humans Country/Region as subject: America do norte Language: En Journal: Clin Pharmacol Ther Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States

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