Treatment of acute gout in hospitalized patients.
J Rheumatol
; 34(7): 1566-8, 2007 Jul.
Article
in En
| MEDLINE
| ID: mdl-17610315
ABSTRACT
OBJECTIVE:
To record practice patterns of treatment of acute gout in hospitalized patients.METHODS:
We performed a retrospective chart review of hospitalized patients diagnosed with gout.RESULTS:
Seventy-nine (43%) patients were diagnosed with acute gout during their hospitalization. Fifty-eight (73%) patients with acute gout were found to have a reduction in their glomerular filtration rate. Twenty patients (25%) underwent arthrocentesis. The most widely used drugs for acute gout were colchicine, n = 42 (53%), and nonsteroidal antiinflammatory drugs (NSAID), n = 40 (51%). Combination therapy was used in 52% of patients with acute gout. Thiry-six (86%) patients treated with colchicine and 32 (80%) patients treated with NSAID had renal failure.DISCUSSION:
Crystal analysis, the gold standard for diagnosing gout, was performed in only 25% of patients suspected of acute gout. Combination antiinflammatory agents are used in over 50% of patients despite the absence of evidence to support use of such combinations. Renal failure was present in 73% of patients with acute gout. Colchicine and NSAID should therefore be used with caution in these patients. Practice patterns vary widely and often appear to be in conflict with recommended diagnostic and treatment measures for acute gout.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Anti-Inflammatory Agents, Non-Steroidal
/
Colchicine
/
Gout Suppressants
/
Gout
/
Hospitalization
Type of study:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Aged80
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
J Rheumatol
Year:
2007
Document type:
Article
Affiliation country:
United States