Normal erythropoiesis but severe polyposis and bleeding anemia in Smad4-deficient mice.

Pan, Dejing; Schomber, Tibor; Kalberer, Christian P; Terracciano, Luigi M; Hafen, Katrin; Krenger, Werner; Hao-Shen, Hui; Deng, Chuxia; Skoda, Radek C

Pan, Dejing; Schomber, Tibor; Kalberer, Christian P; Terracciano, Luigi M; Hafen, Katrin; Krenger, Werner; Hao-Shen, Hui; Deng, Chuxia; Skoda, Radek C.

Affiliation

Pan D; Department of Research, Experimental Hematology, University Hospital Basel, Basel, Switzerland.

Blood ; 110(8): 3049-55, 2007 Oct 15.

Article in En | MEDLINE | ID: mdl-17638848

Subject(s)

Anemia/etiology; Erythropoiesis/physiology; Gastrointestinal Hemorrhage/etiology; Intestinal Polyposis/etiology; Smad4 Protein/deficiency; Animals; Bone Marrow Transplantation; Flow Cytometry; Intestinal Polyposis/pathology; Iron Deficiencies; Liver/chemistry; Liver/metabolism; Mice; Mice, Transgenic; Polyps/pathology; Reverse Transcriptase Polymerase Chain Reaction; Stomach Diseases/pathology; Transforming Growth Factor beta/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Intestinal Polyposis / Erythropoiesis / Smad4 Protein / Gastrointestinal Hemorrhage / Anemia Limits: Animals Language: En Journal: Blood Year: 2007 Document type: Article Affiliation country: Switzerland Country of publication: United States

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