Successful treatment with rituximab in a patient with mental nerve neuropathy in primary Sjögren's syndrome.
Rheumatol Int
; 28(2): 175-7, 2007 Dec.
Article
in En
| MEDLINE
| ID: mdl-17641898
ABSTRACT
We present the case of a 79-year-old female patient with chronic obstructive pulmonary disease on home oxygen therapy who was diagnosed as having Sjögren's syndrome with arthralgias and painful sensory neuropathy. She subsequently developed bilateral numb chin syndrome. Because of refractory and disabling symptoms under high corticosteroids and severe chronic obstructive pulmonary disease, we decided to treat her with rituximab rather than immunosuppressants. This resulted in significant subjective improvement in sicca syndrome while arthalgias, distal and chin paresthesias resolved completely. To our knowledge this is the first description of such a case.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sjogren's Syndrome
/
Sensation Disorders
/
Peripheral Nervous System Diseases
/
Antirheumatic Agents
/
Antibodies, Monoclonal
Limits:
Aged
/
Female
/
Humans
Language:
En
Journal:
Rheumatol Int
Year:
2007
Document type:
Article
Affiliation country:
France