Retinoschisin gene therapy and natural history in the Rs1h-KO mouse: long-term rescue from retinal degeneration.

Kjellstrom, Sten; Bush, Ronald A; Zeng, Yong; Takada, Yuichiro; Sieving, Paul A

Kjellstrom, Sten; Bush, Ronald A; Zeng, Yong; Takada, Yuichiro; Sieving, Paul A.

Affiliation

Kjellstrom S; National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland, USA.

Invest Ophthalmol Vis Sci ; 48(8): 3837-45, 2007 Aug.

Article in En | MEDLINE | ID: mdl-17652759

Subject(s)

Cell Adhesion Molecules/genetics; Eye Proteins/genetics; Genetic Therapy/methods; Retinoschisis/genetics; Retinoschisis/therapy; Age Factors; Animals; Cell Count; Disease Models, Animal; Electroretinography; Gene Transfer Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Retina/pathology; Retina/physiology; Retinoschisis/pathology; Rod Cell Outer Segment/pathology; Rod Cell Outer Segment/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Genetic Therapy / Cell Adhesion Molecules / Retinoschisis / Eye Proteins Type of study: Prognostic_studies Limits: Animals Language: En Journal: Invest Ophthalmol Vis Sci Year: 2007 Document type: Article Affiliation country: United States

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