Lung adenocarcinoma invasion in TGFbetaRII-deficient cells is mediated by CCL5/RANTES.

Borczuk, A C; Papanikolaou, N; Toonkel, R L; Sole, M; Gorenstein, L A; Ginsburg, M E; Sonett, J R; Friedman, R A; Powell, C A

Borczuk, A C; Papanikolaou, N; Toonkel, R L; Sole, M; Gorenstein, L A; Ginsburg, M E; Sonett, J R; Friedman, R A; Powell, C A.

Affiliation

Borczuk AC; Department of Pathology, Columbia University College of Physicians and Surgeons, New York, NY, USA.

Oncogene ; 27(4): 557-64, 2008 Jan 17.

Article in En | MEDLINE | ID: mdl-17653092

Subject(s)

Adenocarcinoma/pathology; Chemokine CCL5/physiology; Lung Neoplasms/pathology; Protein Serine-Threonine Kinases/genetics; Receptors, Transforming Growth Factor beta/genetics; Adenocarcinoma/genetics; Adenocarcinoma/mortality; Chemokine CCL5/genetics; Chemokine CCL5/metabolism; Cohort Studies; Fibroblasts/metabolism; Fibroblasts/pathology; Gene Expression Regulation, Neoplastic/physiology; Humans; Lung Neoplasms/genetics; Lung Neoplasms/mortality; Neoplasm Invasiveness; Receptor, Transforming Growth Factor-beta Type II; Receptors, CCR5/genetics; Receptors, CCR5/metabolism; Stromal Cells/metabolism; Stromal Cells/pathology; Survival Analysis; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenocarcinoma / Protein Serine-Threonine Kinases / Receptors, Transforming Growth Factor beta / Chemokine CCL5 / Lung Neoplasms Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies Limits: Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2008 Document type: Article Affiliation country: United States

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